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1

Manufacturing I-123-labelled radiopharmaceuticals. Pitfalls and solutions

Jos L.H. Eersels, Michael J. Travis, Jacobus D.M. Herscheid

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2005

Language:

english

File:

PDF, 168 KB

english, 2005

2

Fluorination and fluorodemercuration of aromatic compounds with acetyl hypofluorite

Visser, Gerard W. M., Bakker, Cees N. M., Van Halteren, Bert W., Herscheid, Jacobus D. M., Brinkman, Gerard A., Hoekstra, Arend

Journal:

Journal of Organic Chemistry

Year:

1986

Language:

english

File:

PDF, 574 KB

english, 1986

3

Reductive N-alkylation of secondary amines with [2-11C]acetone

Margaretha van der Meij, Nicholas I. Carruthers, Jacobus D.M. Herscheid, Jill A. Jablonowski, Josee E. Leysen, Albert D. Windhorst

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2003

Language:

english

File:

PDF, 116 KB

english, 2003

4

Fluorinated pyrimidines. Part 4. Synthesis, properties and stereochemical conversion of the cis and trans isomers of 6-alkoxy-5-fluoro-5,6-dihydrouracils

Visser, Gerard W. M., Wedzinga, Rinny, Klok, Robert P., Herscheid, Jacobus D. M.

Journal:

Journal of the Chemical Society Perkin Transactions 2

Year:

1994

Language:

english

File:

PDF, 829 KB

english, 1994

5

A facile method for the labeling of proteins with zirconium isotopes

Wilma E. Meijs, Hidde J. Haisma, Roel Van Der Schors, René Wijbrandts, Karin Van Den Oever, Rob P. Klok, Herbert M. Pinedo, Jacobus D.M. Herscheid

Journal:

Nuclear Medicine and Biology

Year:

1996

Language:

english

File:

PDF, 874 KB

english, 1996

6

Synthesis of 18F-labelled 2-fluoro-1,4-quinones using acetylhypofluorite

Jacobus D.M. Herscheid, Rinny Wedzinga, Willem Verboom, Gerard W.M. Visser

Journal:

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes

Year:

1988

Language:

english

File:

PDF, 365 KB

english, 1988

7

Vesamicol and some of its derivatives: Questionable ligands for selectively labelling acetylcholine transporters in rat brain

Franciscus G.J Custers, Josée E Leysen, Johannes C Stoof, Jacobus D.M Herscheid

Journal:

European Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 139 KB

english, 1997

8

Gliotoxin analogs as inhibitors of reverse transcriptase. 1. Effect of lipophilicity

Ottenheijm, Harry C. J., Herscheid, Jacobus D. M., Tijhuis, Marian W., Oosterbaan, Marijn, De Clercq, Erik

Journal:

Journal of Medicinal Chemistry

Year:

1978

Language:

english

File:

PDF, 583 KB

english, 1978

9

N-succinyldesferrioxamine B: A potential radiopharmaceutical for assessing renal function

Jacobus D. M. Herscheid, Arend Hoekstra, Cornelis M. Vos

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

1984

Language:

english

File:

PDF, 259 KB

english, 1984

10

N-hydroxy .alpha.-amino acids in organic chemistry

Ottenheijm, Harry C. J., Herscheid, Jacobus D. M.

Journal:

Chemical Reviews

Year:

1986

Language:

english

File:

PDF, 1.98 MB

english, 1986

11

Fully automated high yield synthesis of (R)- and (S)-[11C]verapamil for measuring P-glycoprotein function with positron emission tomography

Gert Luurtsema, Albert D. Windhorst, Martien P.J. Mooijer, Jacobus D.M. Herscheid, Adriaan A. Lammertsma, Eric J.F. Franssen

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2002

Language:

english

File:

PDF, 118 KB

english, 2002

12

Evaluation of [18F]VUF 5000 as a potential PET ligand for brain imaging of the histamine H3 receptor

Albert D. Windhorst, Henk Timmerman, Rob P. Klok, Wiro M.P.B. Menge, Rob Leurs, Jacobus D.M. Herscheid

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 396 KB

english, 1999

13

On the stereoselectivity of the reaction of [18F]acetylhypofluorite with glucals

Cornelis J.S. Van Rijn, Jacobus D.M. Herscheid, Gerard W.M. Visser, Arend Hoekstra

Journal:

The International Journal of Applied Radiation and Isotopes

Year:

1985

Language:

english

File:

PDF, 432 KB

english, 1985

14

Synthesis and evaluation of radiolabeled analogs of the antidepressant drug zimelidine as potential SPECT-ligands for the serotonin transporter

Jos L.H. Eersels, Rob P. Klok, Joost Verbeek, Allard J. Jonker, Jacobus D.M. Herscheid

Journal:

Nuclear Medicine and Biology

Year:

2004

Language:

english

File:

PDF, 127 KB

english, 2004

15

Mechanism and stereochemistry of the fluorination of uracil and cytosine using fluorine and acetyl hypofluorite

Visser, Gerard W. M., Boele, Saskia, Van Halteren, Bert W., Knops, Gertrudis H. J. N., Herscheid, Jacobus D. M., Brinkman, Gerard A., Hoekstra, Arend

Journal:

Journal of Organic Chemistry

Year:

1986

Language:

english

File:

PDF, 784 KB

english, 1986

16

Synthesis, in vitro pharmacology and radiosynthesis of N-(cis-4-fluoromethylcycloyhexyl)-4-(1(H)-imidazol-4-yl)piperidine-11-thiocarbonamide (VUF 5000), a potential PET ligand for the histamine H3 receptor

Albert D. Windhorst, Henk Timmerman, Wiro M. P. B. Menge, Rob Leurs, Jacobus D. M. Herscheid

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1999

File:

PDF, 501 KB

1999

17

Fluorination of pyrimidines. Part 2. Mechanistic aspects of the reaction of acetyl hypofluorite with uracil and cytosine derivatives

Visser, Gerard W. M., Herder, Renella E., de Kanter, Frans J. J., Herscheid, Jacobus D. M.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1988

Language:

english

File:

PDF, 517 KB

english, 1988

18

Reaction of acetyl hypofluorite with pyrimidines. Part 3. Synthesis, stereochemistry, and properties of 5-fluoro-5,6-dihydropyrimidine nucleosides

Visser, Gerard W. M., Herder, Renella E., Noordhuis, Paul, Zwaagstra, Oene, Herscheid, Jacobus D. M., de Kanter, Frans J. J.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1988

Language:

english

File:

PDF, 1021 KB

english, 1988

19

A Practical Synthesis of N -Hydroxy-α-amino Acid Derivatives

Tijhuis, Marian W., Herscheid, Jacobus D. M., Ottenheijm, Harry C. J.

Journal:

Year:

1980

File:

PDF, 211 KB

1980

20

Reaction of acetyl hypofluorite with aromatic mercury compounds: a new selective fluorination method

Visser, Gerard W. M., v. Halteren, Bert W., Herscheid, Jacobus D. M., Brinkman, Gerard A., Hoekstra, Arend

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1984

Language:

english

File:

PDF, 161 KB

english, 1984

21

One-pot synthesis of [11C]ureas via triphenylphosphinimines

Erica W. van Tilburg, Albert D. Windhorst, Margreet van der Mey, Jacobus D. M. Herscheid

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

2006

Language:

english

File:

PDF, 148 KB

english, 2006

22

A simplified synthesis of 18F-labelled cytosine- and uracil-nucleosides

Gerard W.M. Visser, Paul Noordhuis, Oene Zwaagstra, Jacobus D.M. Herscheid, Arend Hoekstra

Journal:

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes

Year:

1986

Language:

english

File:

PDF, 170 KB

english, 1986

23

Synthesis of dehydroamino acids and didehydrodioxopiperazines and their conversion into α-mercapto-α-amino acid derivatives

Jacobus D. M. Herscheid, Henk P. H. Scholten, Marian W. Tijhuis, Harry C. J. Ottenheijm

Journal:

Recueil des Travaux Chimiques des Pays-Bas

Year:

1981

Language:

english

File:

PDF, 600 KB

english, 1981

24

A simple and efficient method to remove free radioiodide from *I-radiopharmaceuticals

Jos L. H. Eersels, Franciscus G. J. Custers, Geert J. Ensing, Jacobus D. M. Herscheid

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

1995

Language:

english

File:

PDF, 224 KB

english, 1995

25

Biosynthesis of gliotoxin. Synthesis of sulfur-bridged dioxopiperazines from N-hydroxyamino acids

Herscheid, Jacobus D. M., Nivard, Rutger J. F., Tijhuis, Marian W., Ottenheijm, Harry C. J.

Journal:

Journal of Organic Chemistry

Year:

1980

Language:

english

File:

PDF, 564 KB

english, 1980

26

Radiosynthesis and biodistribution of a histamine H3 receptor antagonist 4-[3-(4-piperidin-1-yl-but-1-ynyl)-[11C]benzyl]-morpholine: evaluation of a potential PET ligand

Anu J. Airaksinen, Jill A. Jablonowski, Margreet van der Mey, Ann J. Barbier, Rob P. Klok, Joost Verbeek, Robert Schuit, Jacobus D.M. Herscheid, Josee E. Leysen, Nicholas I. Carruthers, Adriaan A. Lam

Journal:

Nuclear Medicine and Biology

Year:

2006

Language:

english

File:

PDF, 526 KB

english, 2006

27

Approaches to analogs of dehydrogliotoxin. 6. An efficient synthesis of a gliotoxin analog with anti-reverse transcriptase activity

Ottenheijm, Henricus C. J., Herscheid, Jacobus D. M., Kerkhoff, Gerardus P. C., Spande, Tom F.

Journal:

Journal of Organic Chemistry

Year:

1976

Language:

english

File:

PDF, 842 KB

english, 1976

28

N-Hydroxytryptophan in the synthesis of natural products containing oxidized dioxopiperazines. An approach to the neoechinulin and sporidesmin series

Ottenheijm, Harry C. J., Plate, Ralf, Noordik, Jan H., Herscheid, Jacobus D. M.

Journal:

Journal of Organic Chemistry

Year:

1982

Language:

english

File:

PDF, 1.06 MB

english, 1982

29

Synthesis of 18F-labelled VP 16-213 and podophyllotoxin using acetyl hypofluorite

Gerard W.M. Visser, Anita T. Bijma, Jessica A.R. Dijksman, Jacobus D.M. Herscheid

Journal:

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes

Year:

1989

Language:

english

File:

PDF, 482 KB

english, 1989

30

Synthesis of [11C]cyanamide, a versatile synthon for the production of 11C-labelled radiopharmaceuticals

Perry S. Kruijer, Peter J. van Leuffen, Jacobus D.M. Herscheid

Journal:

Applied Radiation and Isotopes

Year:

1996

Language:

english

File:

PDF, 387 KB

english, 1996

31

Production of highly pure no-carrier added 89Zr for the labelling of antibodies with a positron emitter

Wilma E. Meijs, Jacobus D.M. Herscheid, Hidde J. Haisma, Rene Wijbrandts, Frans van Langevelde, Peter J. Van Leuffen, Roel Mooy, Herbert M. Pinedo

Journal:

Applied Radiation and Isotopes

Year:

1994

Language:

english

File:

PDF, 510 KB

english, 1994

32

An optimized synthesis of18F-labelled 5-fluorouracil and a reevaluation of its use as a prognostic agent

Gerard W. M. Visser, Geertrui C. M. Gorree, Boudewijn J. M. Braakhuis, Jacobus D. M. Herscheid

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

1989

Language:

english

File:

PDF, 554 KB

english, 1989

33

.alpha.-Functionalized amino acid derivatives. A synthetic approach of possible biogenetic importance

Herscheid, Jacobus D. M., Nivard, Rutger J. F., Tijhuis, Marian W., Scholten, Henk P. H., Ottenheijm, Harry C. J.

Journal:

Journal of Organic Chemistry

Year:

1980

Language:

english

File:

PDF, 887 KB

english, 1980

34

Evaluation of desferal as a bifunctional chelating agent for labeling antibodies with Zr-89

Wilma E. Meijs, Jacobus D.M. Herscheid, Hidde J. Haisma, Herbert M. Pinedo

Journal:

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes

Year:

1992

Language:

english

File:

PDF, 472 KB

english, 1992

35

Characterization of the Binding Site of the Histamine H 3 Receptor. 2. Synthesis, in Vitro Pharmacology, and QSAR of a Series of Monosubstituted Benzyl Analogues of Thioperamide

Windhorst, Albert D., Timmerman, Henk, Worthington, Edward A., Bijloo, Greetje J., Nederkoorn, Paul H. J., Menge, Wiro M. P. B., Leurs, Rob, Herscheid, Jacobus D. M.

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 133 KB

english, 2000

36

1,4-Dihydroxy-2,5-dioxopiperazines from activated N-hydroxyamino acids

Herscheid, Jacobus D. M., Colstee, J. Hans, Ottenheijm, Harry C. J.

Journal:

Journal of Organic Chemistry

Year:

1981

Language:

english

File:

PDF, 456 KB

english, 1981

37

Gliotoxin analogs as inhibitors of reverse transcriptase. 2. Resolution and x-ray crystal structure determination

Ottenheijm, Harry C. J., Herscheid, Jacobus D. M., Tijhuis, Marian W., Nivard, Rutger J. F., De Clercq, Erik, Prick, Peter A. J.

Journal:

Journal of Medicinal Chemistry

Year:

1978

Language:

english

File:

PDF, 790 KB

english, 1978

38

Manganese-52m for direct application: A new 52Fe/52mMn generator based on a hydroxamate resin

Jacobus D.M. Herscheid, Cornelis M. Vos, Arend Hoekstra

Journal:

The International Journal of Applied Radiation and Isotopes

Year:

1983

Language:

english

File:

PDF, 234 KB

english, 1983

39

Feasibility of planar myocardial carbon 11-acetate imaging

Lucas J. Klein, Frans C. Visser, S.Azam Nurmohamed, Aryan Vink, Job H. Peters, Paul Knaapen, Perry S. Kruijer b, Jacobus D.M. Herscheid, Gerrit J.J. Teule, Cees A. Visser

Journal:

Journal of Nuclear Cardiology

Year:

2000

Language:

english

File:

PDF, 91 KB

english, 2000

40

On the mechanism of gallium accumulation in tumours. Isolation of N-hydroxypeptides

Herscheid, Jacobus D.M., Knops, Gertrudis H.J.N., Boele, Saskia, Hoekstra, Arend

Journal:

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology

Year:

1986

Language:

english

File:

PDF, 299 KB

english, 1986

41

Approaches to the resolution of racemic cyclic disulfides. Application to an epidithiodioxopiperazine

Ottenheijm, Henricus C. J., Herscheid, Jacobus D. M., Nivard, Rutger J. F.

Journal:

Journal of Organic Chemistry

Year:

1977

Language:

english

File:

PDF, 197 KB

english, 1977

42

The in vitro and in vivo behaviour of 18F-labelled 5-fluoro-5,6-dihydrouracil nucleosides

Visser, Gerard W.M., Bijma, Anita T., Dijksman, Jessica A.R., Gorree, Geertrui C.M., Van Walsum, Marijke, Herscheid, Jacobus D.M.

Journal:

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology

Year:

1989

Language:

english

File:

PDF, 651 KB

english, 1989

43

Demethylation and auto-oxidation of different Cobalt-Bleomycin complexes.

VOS, CORNELIS M., SCHIPPER, DICK, HERSCHEID, JACOBUS D. M., WESTERA, GERRIT

Journal:

The Journal of Antibiotics

Year:

1982

Language:

english

File:

PDF, 2.33 MB

english, 1982

44

Tissue distribution of [18F]-5-fluorouracil in mice: effects of route of administration, strain, tumour and dose

Gerard W. M. Visser, Geertrui C. M. Gorree, Godefridus J. Peters, Jacobus D. M. Herscheid

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1990

Language:

english

File:

PDF, 519 KB

english, 1990

45

18F-radiopharmacokinetics of [18F]-5-fluorouracil in a mouse bearing two Colon tumors with a different 5-fluorouracil sensitivity: A study for a correlation with oncological results

Gerard W.M. Visser, Clasina L. van der Wilt, Rinny Wedzinga, Godefridus J. Peters, Jacobus D.M. Herscheid

Journal:

Nuclear Medicine and Biology

Year:

1996

Language:

english

File:

PDF, 1.08 MB

english, 1996

46

A practical method for the preparation of [11C]acetate

Perry S. Kruijer, Tom Ter Linden, Roel Mooij, Frans C. Visser, Jacobus D.M. Herscheid

Journal:

Applied Radiation and Isotopes

Year:

1995

Language:

english

File:

PDF, 422 KB

english, 1995

47

Biodistribution of 123I-Labeled 4-hydroxytamoxifen derivatives in rats with dimethylbenzanthracene-induced mammary carcinomas

Marinus A. Blankenstein, Jan-Henk Voskuil, J.Fred Verzeijlbergen, Geert J. Ensing, Jacobus D.M. Herscheid

Journal:

Nuclear Medicine and Biology

Year:

1997

Language:

english

File:

PDF, 361 KB

english, 1997

48

Desulfurization of epidithiodioxopiperazines. A mechanistic and chiroptical study

Herscheid, Jacobus D. M., Tijhuis, Marian W., Noordik, Jan H., Ottenheijm, Harry C. J.

Journal:

Journal of the American Chemical Society

Year:

1979

Language:

english

File:

PDF, 498 KB

english, 1979

49

Development and characterization of [123I]iodotiagabine for in-vivo GABA-transporter imaging

Schijns, Olaf, van Kroonenburgh, Marinus, Beekman, Freek, Verbeek, Joost, Herscheid, Jacobus, Rijkers, Kim, Visser-Vandewalle, Veerle, Hoogland, Govert

Journal:

Nuclear Medicine Communications

Year:

2013

Language:

english

File:

PDF, 324 KB

english, 2013

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